Pharmaceutical traceability for serialized product records and partner data.
Explore Connect RXAS2 VS. SFTP
AS2 vs. SFTP.
Choose the right connection.
Compare AS2 and SFTP requirements for business file exchange, including endpoint setup, authentication and the evidence needed after delivery.

DATA
FURTHER
GOOD
01 / THE WORK, MADE CLEAR
The partner agreement comes first.
AS2 and SFTP are different approaches to exchanging data. Start with the interface your partner requires, the way each side operates it and the response expected after a transfer. A protocol choice should reflect those requirements, not a claim that one method is best for every workflow.
- 01
Partner requirement
Identify the protocol and connection details the partner accepts.
- 02
Authentication
Agree the appropriate keys, certificates or credentials.
- 03
Completion evidence
Define how receipt and downstream processing will be confirmed.
02 / THE CONNECTION THAT MATTERS
Compare the handoff requirements.
| Context | What matters | The handoff |
|---|---|---|
| AS2 | HTTP-based business-message exchange | Agreed MDN behavior |
| SFTP | File transfer over an SSH connection | Transfer result and destination workflow |
| Either approach | File delivery and application use remain distinct | Business-response requirements |

03 / BUILT AROUND YOUR WORK
Test more than a successful connection.
A connection test shows that systems can communicate. It does not show that the destination can use a specific file or recover from a repeated submission. Include a representative file and a defined failure in the evaluation. Confirm protocol availability and operational controls with the implementation team.
Start a focused conversationA CLEARER PICTURE
Good questions.
Clear answers.
Can the business file contain EDI with either approach?
The transport method and document format address different tasks. The partner agreement determines which combinations are accepted.
Should we select a protocol before talking to the partner?
Collect the partner’s endpoint and security requirements first. They are necessary inputs to a realistic connection design.
ONE FAMILY. FOCUSED PRODUCTS.
Built for what connects.
Read EDI business documents and prepare their data for the systems you use.
Explore EDI ParseXLET’S CONNECT
Bring your file exchange.
Let’s make the next step clear.
Your systems. Your partners. The task your business needs to complete.
Discuss your workflow